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FACTS & FIGURES

Start Date
End Date
Call
IMI2 - Call 14
Grant agreement number
831472

Type of Action: 
RIA (Research and Innovation Action)

Contributions
IMI Funding
8 000 000
EFPIA in kind
10 000 000
Other
410 465
Total Cost
18 410 465

Summary

The vast amounts of data generated during drug discovery are not always used optimally, meaning scientists miss out on opportunities to make new discoveries using old data. One challenge lies in the fact that much of this data is owned by companies, and making it readily available to others would affect their competitiveness.

The MELLODDY project aims to establish a machine learning platform that would make it possible to learn from multiple sets of proprietary data while respecting their highly confidential nature, as data and asset owners will retain control of their information throughout the project.

Through this innovative, blockchain-based solution, the pharmaceutical companies in the project aim to demonstrate the feasibility of this approach with an unprecedented volume of competitive data in the form of over a billion drug-development-relevant data points, and hundreds of terabytes of image data that annotate the biological effects of more than 10 million small molecules. The platform would also take a federated machine learning approach, meaning that the learning effort is not centralised but spread over different, physically separated partners.

The hope is that this solution will deliver insights that will advance drug development by making it easier to identify which small molecules show the most promise for further research.

Participants Show participants on map

EFPIA companies
  • Amgen Research (Munich) GMBH, Munchen, Germany
  • Astellas Pharma Europe BV, Leiden, Netherlands
  • Astrazeneca AB, Södertälje, Sweden
  • Bayer Aktiengesellschaft, Leverkusen, Germany
  • Boehringer Ingelheim Internationalgmbh, Ingelheim, Germany
  • Glaxosmithkline Research And Development LTD., Brentford, Middlesex, United Kingdom
  • Institut De Recherches Servier, Suresnes, France
  • Janssen Pharmaceutica Nv, Beerse, Belgium
  • Merck Kommanditgesellschaft Auf Aktien, Darmstadt, Germany
  • Novartis Pharma AG, Basel, Switzerland
Universities, research organisations, public bodies, non-profit groups
  • Budapesti Muszaki Es Gazdasagtudomanyi Egyetem, Budapest, Hungary
  • Katholieke Universiteit Leuven, Leuven, Belgium
Small and medium-sized enterprises (SMEs) and mid-sized companies (<€500 m turnover)
  • Iktos, Paris, France
  • Loodse GMBH, Hamburg, Germany
  • Owkin France, Paris, France
  • Substra, Nantes, France
Non EFPIA companies
  • Nvidia Switzerland AG, Zurich, Switzerland

CONTACT

Project coordinator
Mathieu Galtier
OWKIN FRANCE
mathieu.galtier[at]owkin.com