Real world outcomes across the AD spectrum for better care: multi-modal data access platform


Start Date
End Date
IMI2 - Call 6
Grant agreement number

IMI Funding
3 998 250
EFPIA in kind
4 210 843
1 288
Total Cost8 210 381


Alzheimer’s disease is on the rise in our ageing population, and new, effective treatments are urgently needed. Currently, the safety and benefits to patients of potential treatments are assessed in strictly-controlled clinical trials. However, clinical trials do not provide information on the health benefits for patients in their daily lives in the ‘real world’. The ROADMAP project aims to deliver a series of methods and tools that will allow the scalable, transferable integration of data on patient outcomes in the real world. The tools will be developed and tested through pilot projects and will lay the foundations for a Europe-wide platform on real world evidence in Alzheimer’s disease. The project will also deliver tools for patient engagement and address the ethical, legal and social implications of adopting a real world evidence approach to Alzheimer’s disease.

The project is part of IMI’s Big Data for Better Outcomes programme, which aims to facilitate the use of diverse data sources to deliver results that reflect health outcomes of treatments that are meaningful for patients, clinicians, regulators, researchers, healthcare decision-makers, and others.

Participants Show participants on map

EFPIA companies
  • AC Immune SA, Lausanne, Switzerland
  • Biogen Idec Limited, Maidenhead, Berkshire, United Kingdom
  • Eli Lilly and Company Ltd, Basingstoke, United Kingdom
  • F. Hoffmann-La Roche Ltd, Basel, Switzerland
  • GE Healthcare Ltd, Little Chalfont, United Kingdom
  • Janssen Pharmaceutica NV, Beerse, Belgium
  • Novartis Pharma AG, Basel, Switzerland
Universities, research organisations, public bodies, non-profit groups
  • Aarhus Universitet, Aarhus C, Denmark
  • Erasmus Universitair Medisch Centrum Rotterdam, Rotterdam, Netherlands
  • Fundacio Jordi Gol I Gurina, Fundacio Privada Per A La Recerca A L'Atencio Primaria De Salut, Barcelona, Spain
  • Goeteborgs Universitet, Gothenburg, Sweden
  • Københavns Universitet (University of Copenhagen), Copenhagen, Denmark
  • London School of Economics and Political Science, London, United Kingdom
  • National Institute for Health and Care Excellence, Manchester, United Kingdom
  • Rijksuniversiteit Groningen, Groningen, Netherlands
  • Universiteit Maastricht, Maastricht, Netherlands
  • University of Edinburgh, Edinburgh, United Kingdom
  • University of Oxford, Oxford, United Kingdom
  • agentschap College ter Beoordeling van Geneesmiddelen, Utrecht, Netherlands
Small and medium-sized enterprises (SMEs) and mid-sized companies (<€500 m turnover)
  • IXICO Technologies Ltd, London, United Kingdom
  • Synapse Research Management Partners S.L, Barcelona, Spain
Patient organisations
  • Alzheimer Europe, Luxembourg, Luxembourg


Project coordinator
John Gallacher
The Chancellor, Masters and Scholars of the University of Oxford
Project contact