IMI Members
Table of Contents
This page contains scientific publications from the IMI Executive Office and from IMI projects
Articles by the IMI Executive Office and governing bodies
Alternatives to Laboratory Animals (ATLA), Vol. 40 (6), pp. 307-312
Gunn, M. et al. (2013) The rational use of animals in drug development: contribution of the innovative medicines initiative
European Journal of Immunology, Vol. 43 (2), pp. 298-302
Goldman, M. et al. (2013) The Innovative Medicines Initiative moves translational immunology forward
Clinical and Translational Medicine, Vol. 2 (2), published online 15 January 2013
Goldman, M. et al. (2013) Public-private partnerships as driving forces in the quest for innovative medicines
Expert Review of Pharmoeconomics & Outcomes research, Vol.12 (5), pp. 545-548
Laverty, H. et al. (2012) Improving R&D productivity of pharmaceutical companies through public-private partnership: experiences from the Innovative Medicines Initiative
Nature Reviews Drug Discovery, published online 30 March 2012
Denee, T.R. et al. (2012) Measuring the value of public–private partnerships in the pharmaceutical sciences
Nature Medicine, Vol. 18, p. 341
Goldman, M. (2012) Public-private partnerships need honest brokering
Clinical Pharmacology and Therapeutics, Vol. 91 (3), pp. 418-125
Goldman, M. (2012) The Innovative Medicines Initiative: A European Response to the Innovation Challenge
Nature Biotechnology, Vol. 29, pp. 689–690
Strohmeier, R. et al. (2011) IMI moves forward
Nature Reviews Drug Discovery, Vol. 10, pp. 321-322
Goldman, M. (2011) Reflections on the Innovative Medicines Initiative
Nature, Vol. 466, pp. 1040-1041
Goldman, M. and De Rijck, K. (2010) Opinion: Clarifying knowledge ownership in Europe’s medicines initiative
BioVacSafe
Journal of Tropical Pediatrics, Vol. 58 (3), pp. 167-169
Rath, B. et al. (2012) Promoting evidence-based vaccine safety research and communication - the Vienna vaccine safety initiative
Vaccine, Vol. 30 (22), pp. 3255-3265
Muehlhans, S. et al. (2012) Safety reporting in developing country vaccine clinical trials - a systematic review
The International Journal of Tuberculosis and Lung Disease, Vol. 16 (9), pp. 1140-1148(9)
Maertzdorf, J. et al. (2012) Enabling biomarkers for tuberculosis control
Trends in Immunology, Vol. 33 (7), pp. 373-379
Kaufmann, S. et al. (2012) Tuberculosis vaccine development: strength lies in tenacity
Pathogenesis of Encephalitis, Chapter 6, published online 09 December 2011
Rath, B. (2011) The value of standardized case definitions in encephalitis clinical research
Clinical Pediatrics, published online 25 August 2011
Rath, B. et al. (2011) Rotavirus encephalitis with Basal Ganglia involvement in an 8-month-old infant
BTCure
Annals of the Rheumatic Diseases, Vol. 72 (1), pp. 148-150
Shi, J. et al. (2013) Recognition of citrullinated and carbamylated proteins by human antibodies: specificity, cross-reactivity and the 'AMC-Senshu' method
Annals of the Rheumatic Diseases, Vol. 71 (6), pp. 1088-1093
Klarenbeek, P. L. et al. (2012) Inflamed target tissue provides a specific niche for highly expanded T-cell clones in early human autoimmune disease
Autoimmunity, Vol. 45 (8), 602-611
Herman, S. et al. (2012) Cell death and cytokine production induced by autoimmunogenic hydrocarbon oils
Arthritis and Rheumatism, Vol. 64 (6), pp. 1838-1847
Abdollahi-Roodsaz, S. et al. (2012) Destructive role of myeloid differentiation factor 88 and protective role of TRIF in interleukin-17-dependent arthritis in mice
Bioethics, published online 10 June 2012
Johnsson, L. et al. (2012) Adequate trust avails, mistaken trust matters: on the moral responsibility of doctors as proxies for patients' trust in biobank research
Biopreservation and Biobanking, Vol. 10 (1), pp. 45-47
Evers, K. et al. (2012) Commercialization of biobanks
Cancer Epidemiology, Vol. 36 (6), pp. 575-578
Hansson, M. et al. (2012) Medical registries represent vital patient interests and should not be dismantled by stricter regulation
Gut, published online 27 June 2012
Gunther, C. et al. (2012) Apoptosis, necrosis and necroptosis: cell death regulation in the intestinal epithelium
Arthritis Research & Therapy, Vol. 14 (6), p. 227
Klein, K. et al. (2012) Epigenetic contributions in the development of rheumatoid arthritis
Annals of the Rheumatic Diseases, published online 1 June 2012
Lundberg, K. et al. (2012) Genetic and environmental determinants for disease risk in subsets of rheumatoid arthritis defined by the anticitrullinated protein/peptide antibody fine specificity profile
Nature Immunology, Vol. 13, pp. 1213-1221
Le Friec, G. et al. (2012) The CD46-Jagged1 interaction is critical for human TH1 immunity
Annals of the Rheumatic Diseases, published online 2 March 2012
Gerlag, D. et al. (2012) EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis
PLoS ONE, Vol. 7 (11), e49214
García-Bermúdez, M. et al. (2012) Study of association of CD40-CD154 gene polymorphisms with disease susceptibility and cardiovascular risk in Spanish rheumatoid arthritis patients
Nature Reviews Rheumatology, Vol. 8, pp. 656-664
Schett, G. et al. (2012) Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment
Annals of the Rheumatic Diseases, Vol. 71 (12), pp. 1921-1923
Raza, K. et al. (2012) Timing the therapeutic window of opportunity in early rheumatoid arthritis: proposal for definitions of disease duration in clinical trials
The Journal of Clinical Investigation, Vol. 122 (11), pp. 4231-4242
Koliaraki, V. et al. (2012) Tpl2 regulates intestinal myofibroblast HGF release to suppress colitis-associated tumorigenesis
Arthritis and Rheumatism, Vol. 64 (11), pp. 3594-3603
Förster, M. et al. (2012) Genetic control of antibody production during collagen-induced arthritis development in heterogeneous stock mice
Journal of Molecular Medicine, Vol. 90 (11), pp. 1295-1309
Smiljanovic, B. et al. (2012) The multifaceted balance of TNF-α and type I/II interferon responses in SLE and RA: how monocytes manage the impact of cytokines
Clinical and Experimental Rheumatology, Vol. 30 (3), pp. 429-435
Goëb, V. et al. (2012) Potential role of arthroscopy in the management of inflammatory arthritis
Arthritis and Rheumatism, Vol. 64 (8), pp. 2482-2488
Snir, O. et al. (2012) Multifunctional T cell reactivity with native and glycosylated type II collagen in rheumatoid arthritis
PLoS ONE, Vol. 7 (8), e43661
Lamana, A. et al. (2012) The TT genotype of the STAT4 rs7574865 polymorphism is associated with high disease activity and disability in patients with early arthritis
Journal of Experimental Medicine, Vol. 209, pp. 925-933
Nikitopoulou, I. et al. (2012) Autotaxin expression from synovial fibroblasts is essential for the pathogenesis of modeled arthritis
Annals of the Rheumatic Diseases, published online May 2012
Pandis, I. et al. (2012) Identification of microRNA-221/222 and microRNA-323-3p association with rheumatoid arthritis ia predictions using the human tumour necrosis factor transgenic mouse model
Journal of Rheumatology, Vol. 39, pp. 679-685
Makrygiannakis, D. et al. (2012) Apoptosis as a mechanism of action of tumor necrosis factor antagonists in rheumatoid arthritis
The Journal of Clinical Investigation, Vol. 122, pp. 1791-1802
Harre, U. et al. (2012) Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin
Arthritis & Rheumatism, Vol. 64, pp. 1323-1328
Suwannalai, P. et al. (2012) Avidity maturation of anti-citrullinated protein antibodies in rheumatoid arthritis
Arthritis & Rheumatism, Vol. 64, pp. 1762-1770
Koenders, M.I. et al. (2012) T cell lessons from the rheumatoid arthritis synovium SCID mouse model: CD3-rich synovium lacks response to CTLA-4Ig but is successfully treated by interleukin-17 neutralization
Arthritis & Rheumatism, published online 5 March 2012
Snir, O. et al. (2012) Multifunctional T cell reactivity to native and glycosylated type-II collagen in rheumatoid arthritis
Archives of Disease in Childhood, published online 22 February
Hansson, M.G. et al. (2012) Ethics bureaucracy: a significant hurdle for collaborative follow-up of drug effectiveness in rare childhood diseases
Arthritis Research & Therapy, Vol. 13 (6), R195
Suwannalai, P. et al. (2011) The fine specificity of IgM anti-citrullinated protein antibodies (ACPA) is different from that of IgG ACPA
Annals of the Rheumatic Diseases, Vol. 70, pp. 2184-2190
Vazgiourakis, V. M. et al. (2011) A common SNP in the CD40 region is associated with systemic lupus erythematosus and correlates with altered CD40 expression: implications for the pathogenesis
Annals of the Rheumatic Diseases, published online 13 October 2011
Willemze, A. et al. (2011) The ACPA recognition profile and subgrouping of ACPA-positive RA patients
Proceedings of the National Academy of Sciences, Vol. 108 (42), pp. 17372-17377
Shi, J. et al. (2011) Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage
Trends in Immunology, Vol. 32 (6), pp. 278-286
Cope, A. et al. (2011) The Th1 life cycle: molecular control of IFN-γ to IL-10 switching
DDMoRe
AAPS Journal, 15 (1), pp. 183-194
Parra-Guillen, Z.P. et al. (2013) Target-mediated disposition model describing the dynamics of il12 and ifn gamma after administration of a mifepristone-inducible adenoviral vector for il-12 expression in mice
Human Mutation, Vol. 33 (5), pp. 837-848
De Bono, B. et al. (2012) ApiNATOMY: a novel toolkit for visualizing multiscale anatomy schematics with phenotype-related information
IEEE Transactions on Biomedical Engineering, Vol. 59 (8), pp. 2161-2170
Magni, P. et al. (2012) A minimal model of tumor growth inhibition in combination regimens under the hypothesis of no interaction between drugs
Human Mutation, Vol. 33, pp. 837-848
De Bono, B. et al. (2012) ApiNATOMY: a novel toolkit for visualizing multiscale anatomy schematics with phenotype-related information
BMC Research Notes, Vol. 4 (1), p. 313
De Bono, B. et al. (2011) The RICORDO approach to semantic interoperability for biomedical data and models: strategy, standards and solutions
EHR4CR
iHealth Connections, ;1(2):108–13, published on-line.
Kalra, D. et al. (2011) Case Report from the EHR4CR Project—A European Survey on Electronic Health Records Systems for Clinical Research
EMTRAIN
European Journal of Pharmaceutical Sciences, 45 (5), pp. 515-520
Klech, H. et al. (2012) European initiative towards quality standards in education and training for discovery, development and use of medicines
eTOX
Molecular Informatics, Vol. 32 (1), pp. 24-35
Cases, M. et al. (2013) The eTOX library of public resources for in silico toxicity prediction
Trends in Genetics, published online 6 December 2012
Furlong, L.I. (2012) Human diseases through the lens of network biology
Altex, Vol. 29 (2), pp. 129-137
Hardy, B. et al. (2012) Food for thought ... a toxicology ontology roadmap
SAR and QSAR in Environmental Research, Vol. 23 (5-6), pp. 435-459
Przybylak, K.R. et al. (2012) Assessing toxicological data quality: basic principles, existing schemes and current limitations
Molecular Informatics, Vol. 31 (8), pp. 599-609
Zdrazil, B. et al. (2012) Annotating human P-Glycoprotein bioassay data
Molecular Informatics, Vol. 31 (8), pp. 547-553
Pinto, M. et al. (2012) An in silico classification model for putative ABCC2 substrates
PLoS Computational Biology, Vol. 8, e1002457
Bauer-Mehren, A. et al. (2012) Automatic Filtering and Substantiation of Drug Safety Signals
Journal of Biomedical Informatics, published online April 2012
Van Mulligen, E. M. et al. (2012) The EU-ADR corpus: annotated drugs, diseases, targets, and their relationships
International Journal of Molecular Sciences, Vol. 13 (3), pp. 3820-3846
Briggs, K. et al. (2012) Inroads to predict in vivo toxicology - an introduction to the eTOX project
Bioorganic and Medicinal Chemistry, published online March 2012
Poongavanam, V. et al. (2012) Fingerprint-based in silico models for the prediction of P-glycoprotein substrates and inhibitors
Expert Opinion on Drug Metabolism & Toxicology, Vol. 8, No.2, pp. 201-217
Przybylak, K.R. et al. (2012) In silico models for drug-induced liver injury--current status
ALTEX, Vol 29, pp. 139-156
Hardy, B. et al. (2012) Toxicology ontology perspectives
SAR and QSAR in Environmental Research, Vol. 23, pp. 221-235
Panagiotou, G. et al. (2012) The impact of network biology in pharmacology and toxicology
Journal of Pharmacogenomics and Pharmacoproteomics, S7:001, doi: 10.4172/2153-0645.S7-001
Taboureau, O. et al. (2012) Toxicogenomics Investigation Under the eTOX Project
Toxicological Sciences, Vol. 126, pp. 275-284
Parkinson, J. et al. (2012) Application of data mining and visualization techniques for the prediction of drug-induced nausea in man
PLOS Computational Biology, Vol. 7, e1002036
Klepsch, F. et al. (2011) Exhaustive sampling of docking poses reveals binding hypotheses for propafenone type inhibitors of P-glycoprotein
Future Medicinal Chemistry, Vol. 3, pp. 1117-1128
Schwaha, R. et al. (2011) Use of shape similarities for the classification of P-glycoprotein substrates and nonsubstrates
Expert Opinion on Drug Metabolism and Toxicology, Vol. 7, pp. 1481-1495
Ellison, C. M. et al. (2011) A review of the use of in silico methods to predict the chemistry of molecular initiating events related to drug toxicity
BMC Bioinformatics, Vol. 12:S1
Arighi, C. N. Et al. (2011) Overview of the BioCreative III Workshop
Molecular Informatics, Vol. 30, pp. 506-519
Krallinger, M. Et al. (2011) Text Mining for Drugs and Chemical Compounds: Methods, Tools and Applications
Nature Biotechnology, Vol. 29 (9), pp. 789-790
Mestres, J. et al. (2011) Shaping the future of safer innovative drugs in Europe
Environmental Health Perspectives, published online 17 August 2011
Audouze K. & Grandjean P. (2011) Application of computational systems biology to explore environmental toxicity hazards
Critical Reviews in Toxicology, Vol. 41 (9), pp. 783-802
Enoch, S. J. et al. (2011) A review of the electrophilic reaction chemistry involved in covalent protein binding relevant to toxicity
PLoS ONE, Vol. 6 (6), e20284
Bauer-Mehren A. et al. (2011) Gene-Disease Network Analysis Reveals Functional Modules in Mendelian, Complex and Environmental Diseases
Journal of Chemical Information and Modeling, Vol. 51, pp. 483-92
Obiol-Pardo, C. et al. (2011) A Multiscale Simulation System for the Prediction of Drug-Induced Cardiotoxicity
Combinatorial Chemistry & High Throughput Screening, Vol. 14, No 5, pp. 375-387
Taboureau, O. and Jørgensen, F.S. (2011) In silico predictions of hERG channel blockers in drug discovery: From ligand-based and target-based approaches to systems chemical biology
Nucleic Acids Research, Vol. 9 (Suppl. 1): D367-D372
Taboureau, O. et al. (2011) ChemProt: a disease chemical biology database
Bioinformatics, Vol. 26, pp. 2924-2926
Bauer-Mehren, A. et al. (2010) DisGeNET - a Cytoscape plugin to visualize, integrate, search and analyze gene-disease networks
Expert Opinion on Drug Metabolism & Toxicology, Vol. 6, pp. 1253-1263
Garcia-Serna, R. and Mestres, J. (2010) Anticipating drug side effects by comparative pharmacology
Molecular Informatics, Vol. 29, pp. 543-551
Vidal, D. and Mestres, J. (2010) In silico receptorome screening of antipsychotic drugs
PLoS Computational Biology, Vol. 6(5): e1000788
Audouze, K. et al. (2010) Deciphering diseases and biological targets for environmental chemicals using toxicogenomics networks
Eu2P
Nature Genetics, Vol. 44, pp. 552-561
Stein, J.L. et al. (2012) Identification of common variants associated with human hippocampal and intracranial volumes
Nature Neuroscience, Vol. 15, pp. 920-925
Whelan, R. et al. (2012) Adolescent impulsivity phenotypes characterized by distinct brain networks
European Journal of Pharmaceutical Sciences, 45 (5), pp. 515-520
Klech, H. et al. (2012) European initiative towards quality standards in education and training for discovery, development and use of medicines
EU-AIMS
PNAS, Vol. 110 (2), pp. 725-730
Budreck, E.C. et al. (2012) Neuroligin-1 controls synaptic abundance of NMDA-type glutamate receptors through extracellular coupling
Archives General Psychiatry, Vol.69 (10), pp. 1003-1013
Daly, E.M. et al. (2012) Serotonin and the neural processing of facial emotions in adults with autism: an fMRI study using acute tryptophan depletion
Nature Neuroscience, Vol. 15 (5), pp. 663-668
Meyer-Lindenberg, A., Tost H. (2012) Neural mechanisms of social risk for psychiatric disorders
PNAS, Vol. 109 (51), pp. 20775-20776
Stacey, D. et al. (2012) RASGRF2 regulates alcohol-induced reinforcement by influencing mesolimbic dopamine neuron activity and dopamine release
Nature Reviews Drug Discovery, Vol. 11 (11), pp. 815-816
Murphy, D. et al. (2012) EU-AIMS: a boost to autism research
Trends in Pharmacological Sciences, Vol. 33 (12), pp. 669-684
Spooren, W. et al. (2012) Synapse dysfunction in autism: a molecular medicine approach to drug discovery in neurodevelopmental disorders
Journal of Neural Transmission, Vol. 119 (10), pp. 1111-1120
Wong, C.C.P. et al. (2012) Integration of the circadian and stress systems: influence of neuropeptides and implications for alcohol consumption
Science, published online 13 September 2012
Baudouin, S. J. et al. (2012) Shared Synaptic Pathophysiology in Syndromic and Nonsyndromic Rodent Models of Autism
Nature, Vol. 488, pp. 471-475
Kong, A. et al. (2012) Rate of de novo mutations and the importance of father’s age to disease risk
Nature News Article:Fathers bequeath more mutations as they age
Nature News and Reviews: Genetics: The rate of human mutation
Nature Genetics, Vol. 44, pp. 552-561
Stein, J.L. et al. (2012) Identification of common variants associated with human hippocampal and intracranial volumes
Nature Neuroscience, Vol. 15, pp. 920-925
Whelan, R. et al. (2012) Adolescent impulsivity phenotypes characterized by distinct brain networks
Biochemical Journal, published online 6 Jun 2012
Poulopoulos, A. et al. (2012) Homodimerization and isoform-specific heterodimerization of neuroligins
Molecular Psychiatry, published online 17 July 2012
Ecker, C., et al. (2012) Translational approaches to the biology of Autism: false dawn or a new era?
Europain
Wiley Interdisciplinary Reviews-Systems, Vol. 5 (1), pp. 11-35
Atunes-Martins, A. et al. (2013) Systems biology approaches to finding novel pain mediators
The Lancet Neurology, Vol. 11 (11), pp. 999-1005
Baron, R. et al. (2012) Subgrouping of patients with neuropathic pain according to pain-related sensory abnormalities: a first step to a stratified treatment approach
Acta Oncologica, Vol. 51 (8), pp. 1036-1044
Andersen, K.G. et al. (2012) Persistent pain, sensory disturbances and functional impairment after adjuvant chemotherapy for breast cancer: Cyclophosphamide, epirubicin and fluorouracil compared with docetaxel + epirubicin and cyclophosphamide
Hernia, Vol. 16 (5), pp. 573-577
Bischoff, J. M. et al. (2012) Does nerve identification during open inguinal herniorrhaphy reduce the risk of nerve damage and persistent pain?
Open Biology, Vol. 2 (5), published online 9 May 2012
Quick, K. et al. (2012) TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells
Neuroscience Letters, Vol. 519 (1), pp.31-36
Sikandar, S. et al. (2012) Brainstem facilitations and descending serotonergic controls contribute to visceral nociception but not pregabalin analgesia in rats
Future Virology, Vol. 7 (9), pp. 849-854
Cherry, C.L. et al. (2012) HIV-associated sensory neuropathy: still a problem in the post-stavudine era?
Prostaglandins & Other Lipid Mediators, Vol. 99 (1-2), pp. 15-23
Linke, B. et al. (2012) Analysis of sphingolipid and prostaglandin synthesis during zymosan-induced inflammation
International Psychogeriatrics, Vol. 24, pp. 698-707
Amanzio, M. et al. (2012) A systematic review of adverse events in the placebo arm of donepezil trials: the role of cognitive impairment
PAIN, Vol. 153, pp. 1537-1540
Westermann, A. et al. (2012) Different underlying pain mechanisms despite identical pain characteristics: a case report of a patient with spinal cord injury
PAIN, Vol. 153, pp. 1484-1494
Reiswich, J. et al. (2012) Intact 2D-form recognition despite impaired tactile spatial acuity in complex regional pain syndrome type I
Current Diabetes Reports, Vol. 12, pp. 393-402
Krumova, E.K. et al. (2012) Neuropathic pain: is quantitative sensory testing helpful?
PAIN, Vol. 153, pp. 1292-1300
Petersen, G.L. (2012) Placebo manipulations reduce hyperalgesia in neuropathic pain
CNS Drugs, Vol. 26, pp. 297-307
Häuser, W. et al. (2012) The role of antidepressants in the management of fibromyalgia syndrome: a systematic review and meta-analysis
Lancet Neurology, Vol. 11, pp. 629-642
Calvo, M. et al. (2012) The role of the immune system in the generation of neuropathic pain
Regional Anesthesia & Pain Medicine, May/June 2012, Volume 37, Issue 3, pages 340–343
Werner, M.U. et al. Pulsed Radiofrequency in the Treatment of Persistent Pain After Inguinal Herniotomy: A Systematic Review
European Journal of Pain, Volume 16, Issue 4, pages 485–495
Andrews, N. et al. (2012) Spontaneous burrowing behaviour in the rat is reduced by peripheral nerve injury or inflammation associated pain
Surgical Endoscopy, Volume 26, Number 4, pages 979-983
Bischoff, J.M. et al. (2012) Dysejaculation after laparoscopic inguinal herniorrhaphy: a nationwide questionnaire study
Anesthesia & Analgesia, published online 30 March 2012
Bischoff, J.M. et al. Ultrasound-Guided Ilioinguinal/Iliohypogastric Nerve Blocks for Persistent Inguinal Postherniorrhaphy Pain: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial
Clinical Journal of Pain, Volume 28, Issue 2, pages 136–142
Wildgaard, K. et al (2012) Neurophysiological characterisation of persistent post-thoracotomy pain
The Breast, Volume 21, Issue 1, pages 46–49
Andersen, K.G. et al. (2012) Persistent pain after targeted intraoperative radiotherapy (TARGIT) or external breast radiotherapy for breast cancer: a randomized trial
British Journal of Anaethesia, Volume 108, Issue 1, pages 126-133, published online October 2011
Wildgaard, K.et al. (2012) Quantitative sensory testing of persistent pain after video-assisted thoracic surgery lobectomy
European Journal of Pain Supplements, Volume 4, Issue S4, pages 203–207
Werner, M.U. et al. (2012) Characterization of persistent postoperative pain by quantitative sensory testing
PAIN, Journal for the International Association for the Study of Pain (IASP), Volume 153, Issue 1, pages 42-55
Serra, J. et al. (2012) Microneurographic identification of spontaneous activity in C-nociceptors in neuropathic pain states of humans and rats
PLOS Neglected Tropical Diseases, Vol. 5, e 981
Lasry-Levy, E. (2011) Neuropathic pain and psychological morbidity in patients with treated leprosy: a cross-sectional prevalence study in Mumbai
Neurology, Vol. 77, pp. 1096-1101
Lanz, M. et al.(2011) Bilateral somatosensory cortex disinhibition in complex regional pain syndrome type I
Hernia, Volume 15, Number 5, pages 521-529
Linderoth, G. et al. (2011) Neurophysiological characterisation of persistent pain after laparoscopic inguinal hernia repair
PAIN, Journal for the International Association for the Study of Pain (IASP), Volume 152, Issue 10 , Pages 2312-2322
Sikandar, S. et al. (2011) Pregabalin modulation of spinal and brainstem visceral nociceptive processing
Techniques in Regional Anesthesia and Pain Management, Volume 15, Issue 3, pages 83–89
Wildgaard, K. et al. (2011) Chronic post-thoracotomy pain—What is new in pathogenic mechanisms and strategies for prevention?
The Journal of Pain, Volume 12, Issue 7, pages 725-746
Andersen, K. G. et al. (2011) Persistent pain after breast cancer treatment: A critical review of pathogenic mechanisms and strategies for prevention
Scandinavian Journal of Pain, Volume 2, Issue 3 , pages 139-145
Baastrup, C. et al. (2011) Coexisting mechanical hypersensitivity and anxiety in a rat model of spinal cord injury and the effect of pregabalin, morphine, and midazolam treatment
Science Translational Medicine, Volume 3, Issue 90, pages 90 ra60
Dawes J.M. et al. (2011) CXCL5 mediates UVB irradiation induced pain
NeuroImage, Volume 57, Issue 1, pages 206–213
Riedl, V. et al. (2011) Repeated pain induces adaptations of intrinsic brain activity to reflect past and predict future pain
PAIN, Journal for the International Association for the Study of Pain (IASP), Volume 152, Issue 2, pages 343–353
Serra, J. et al. (2011) Double and triple spikes in C-nociceptors in neuropathic pain states: An additional peripheral mechanism of hyperalgesia
Brain Research, Volume 1370, pages 129–135
Baastrup, C. et al. (2011) Pregabalin attenuates place escape/avoidance behavior in a rat model of spinal cord injury
Acta Anaesthesiologica Scandinavica, Volume 55, Issue 1, pages 60–68
Wildgaard, K. et al. (2011) Consequences of persistent pain after lung cancer surgery: a nationwide questionnaire study
Journal of Pain, Volume 12, Issue 7, Pages 764-773
Binder, A. et al. (2011) Topical high-concentration (40%) menthol-somatosensory profile of a human surrogate pain model
Philosophical Transactions of the Royal Society Biological Sciences, Volume 366 (1572), 1913-1921
Vase, L. et al. (2011) Patients' direct experiences as central elements of placebo analgesia
PLOS One, Vol. 5, e14433
Phillips, T.J. et al. (2010) Pharmacological treatment of painful HIV-associated sensory neuropathy: a systematic review and meta-analysis of randomised controlled trials
PAIN, Journal for the International Association for the Study of Pain (IASP), Volume 151, Issue 3, Pages 670-679
Baastrup, C. et al. (2010) Spinal-, brainstem- and cerebrally mediated responses at- and below-level of a spinal cord contusion in rats: evaluation of pain-like behavior
PAIN, Vol. 150, pp 573-581
Finnerup, N.B. et al. (2010) The evidence for pharmacological treatment of neuropathic pain
Anesthesiology, Volume 112, Issue 4, pages 957-969
Aasvang, E. K. et al. (2010) Predictive Risk Factors for Persistent Postherniotomy Pain
IMIDIA
The Journal of Clinical Investigation, Vol. 122 (11), pp. 4105-4117
Iglesias, J. et al. (2012) PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, Vol. 1823 (10), pp. 1697-1707
Kaminski, M.T. et al. (2012) Real-time analysis of intracellular glucose and calcium in pancreatic beta cells by fluorescence microscopy
American Journal of Physiology: Endocrinology and Metabolism, Vol. 303 (1), pp. 144-151
Carvalho, C.P. et al. (2012) Impaired β-cell-β-cell coupling mediated by Cx36 gap junctions in prediabetic mice
Biochemical Pharmacoplogy, Vol. 83, pp. 1300-1306
Baltrusch, S. et al. (2012) Additive activation of glucokinase by the bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase and the chemical activator LY2121260
PLoS ONE, Vol. 7, Issue 5, ArticleID e36188
Martino, et al. (May 2012) Palmitate Activates Autophagy in INS-1E b-Cells and in Isolated Rat and Human Pancreatic Islets
Diabetes, Vol. 61, pp. 574-585
Noordeen, N.A. et al. (2012) Glucose-induced nuclear shuttling of ChREBP is mediated by sorcin and Ca(2+) ions in pancreatic β-cells
Diabetes, Vol. 60 (11), pp. 2872-2882, published online 27 September 2011
Thorel, F. et al. (2011) Normal glucagon signaling and β-cell function after near-total α-cell ablation in adult mice
Proceedings of the National Academy of Sciences, Vol. 108 (51), pp. 20719-20724
Virostko, J. et al. (2011) Multimodal image coregistration and inducible selective cell ablation to evaluate imaging ligands
Journal of Clinical Investigation, Vol. 121 (12), pp. 4870-4879
Klee, P. et al. (2011) Connexins protect mouse pancreatic beta cells against apoptosis
Journal of Biological Chemistry, published online 7 November 2011
Semplici, F. et al. (2011) A human mutation within the per-ARNT-sim (PAS) domain-containing protein kinase (PASK) causes basal insulin hypersecretion
Diabetologia, Vol 54, pp. 3078-3082
Locke, J. M. Et al. (2011) An alternative polyadenylation signal in TCF7L2 generates isoforms that inhibit T cell factor/lymphoid-enhancer factor (TCF/LEF)-dependent target genes
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